منابع مشابه
Cognitive Effects of Antiepileptic Drugs
Antiepileptic drugs (AEDs) can adversely affect cognitive function by suppressing neuronal excitability or enhancing inhibitory neurotransmission. The main cognitive effects of AEDs are impaired attention, vigilance, and psychomotor speed, but secondary effects can manifest on other cognitive functions. Although the long-term use of AEDs can obviously elicit cognitive dysfunction in epilepsy pa...
متن کاملTeratogenic effects of antiepileptic drugs
The use of older generation antiepileptic drugs (AEDs) during pregnancy is known to be associated with a two- to threefold increased risk of birth defects in the offspring and possible also other adverse outcomes in the exposed infant. Much less has been known about newer generation AEDs in this respect. Recent studies based on national registries as well as specific epilepsy and pregnancy regi...
متن کاملP 146: The Best New Antiepileptic Drugs to Prevent Orofacial Malformations as Side Effects of Antiepileptic Drugs
Mothers exposed to Antiepileptic drugs (AEDs) are at high risk to born babies with orofacial malformations such as cleft lips. About 9 percent of congenital abnormalities in babies of mothers with epilepsy relates to orofacial abnormalities. Maintaining safe antiepileptic drugs for millions of mothers with epilepsy is very important. Researches show that new AEDs have less side effects than the...
متن کاملPrenatal Exposure to Antiepileptic Drugs and Dental Agenesis
OBJECTIVE The aim of the study was to investigate the association between prenatal exposure to AEDs and the risk of dental agenesis and to differentiate between the possible effects of the different drugs used. METHODS Data on 214 exposed and 255 unexposed children, aged 12-18 years, were extracted from the Prescription Database of the Central Denmark Region and North Denmark Region and the D...
متن کاملCognitive side effects of antiepileptic drugs.
All of the established antiepileptic drugs (AEDs) can produce cognitive side effects, which are increased with polypharmacy and with increasing dosage and anticonvulsant blood levels. However, cognitive side effects are usually modest for AED monotherapy with anticonvulsant blood levels within the standard therapeutic ranges. Further, these effects are offset in part by reduced seizure activity...
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ژورنال
عنوان ژورنال: Epilepsy Currents
سال: 2010
ISSN: 1535-7597,1535-7511
DOI: 10.1111/j.1535-7511.2009.01350.x